LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION IN COMORBID CONDITION

Abstract

Changes in the diastolic function of the left ventricle in patients with myocardial infarction, in conditions of acute coronary syndrome, lead to a decrease in the pumping function of the left ventricle or precedes it. The severity of the clinical course and prognosis of congestive heart failure is associated with the occurrence of left ventricular diastolic dysfunction. The role of diastolic dysfunction in the development of the clinic and prognosis of congestive heart failure in patients with acute myocardial infarction with type 2 diabetes mellitus has been little studied [1, 7]. Our study included 55 patients aged 45 to 60 years (48.2±3.5 y.o.) who were admitted to the cardiac intensive care unit with a diagnosis of ACS with further transformation into acute myocardial infarction concomitant with type 2 diabetes mellitus. The patients were divided into two groups depending on the ejection fraction (1st-with EF 45%, 2nd — with EF<45%). The control group consisted of 30 healthy people aged 40 to 55 years (48.9±3.5 y.o.). In the hospital, patients received standard therapy-anticoagulants (heparin), beta-blockers. antiplatelet agents (aspirin), ACE inhibitors, nitrates, insulin therapy, potassium preparations